Blood viscosity and you may blood circulation pressure: character out of temperatures and hyperglycemia

Yildirim Cinar, A beneficial. Mete Senyol, Kamber Duman, Bloodstream viscosity and blood pressure levels: part away from temperature and you may hyperglycemia, Western Diary regarding Blood pressure level, Volume step one4, Matter 5, , Profiles 433–438,

Abstract

We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased http://www.datingranking.net/asian-hookup-apps/ %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P < .001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25% (r = 0.59, P = .002). In this state, blood flow rate decrease was 20% and BP increase for physiological compensation was 25%. Consequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hypertens 2001;–438 © 2001 American Journal of Hypertension, Ltd.

The purpose of our very own research is to look into the matchmaking among heat, sugar concentration, and viscosity away from blood and plasma, also to assess their consequences into blood pressure (BP) centered on Hagen-Poiseuille’s hydrodynamics formula.

If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F₁ ? F₂) (a 2 ? r 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F₁ ? F₂), where ? is the viscosity of the fluid, F₁ and F₂ are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases.

Blood viscosity and you may blood pressure: role out of heat and you will hyperglycemia

It has been shown one between % and you will % values off hematocrit, most of the 11% rise in hematocrit expands bloodstream viscosity by the 20%. Within this state, considering Poiseuille’s picture, circulation speed reduces of the %, that may end in muscle ischemia. To store the fresh new circulatory system in harmony (that’s, keeping new disperse rates adequate and you may blocking tissues ischemia), a beneficial 20% escalation in BP otherwise cuatro.66% vasodilation needs. step 3 However, the human circulatory method is perhaps not a precise signed system, since the blood viscosity is changed with the intake from eating or pills. 4–8 At exactly the same time, the results of dietary fat and of certain medication into blood viscosity and you will hemodynamics for example BP had been claimed. While the atherosclerotic vessels don’t dilate good enough due to the fact a response to vasodilator pills, this has been ideal you to enhanced bloodstream viscosity can simply feel paid having a great BP increase in including circumstances. 9–several As well as, this new dating certainly BP, headache, coagulation, blood flow velocity, and you may bloodstream viscosity was in fact demonstrated via the values off hemodynamics. thirteen, 14

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